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KMID : 1191520180230010015
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Journal of Korean Traditional Oncology
2018 Volume.23 No. 1 p.15 ~ p.21
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A Case Report of FOLFIRI-Induced Diarrhea in Patient with Metastatic Rectal Cancer Treated with Modified Wiryeong-tang
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Yoon Sung-Soo
Kim Eun-Hye
Lee Ji-Young
Yun Seong-Woo
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Abstract
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Objectives : This study was aimed to describe a case of a patient with FOLFIRI-induced diarrhea, which was improved by treatment with Korean herbal medicine, modified Wiryeong-tang.
Methods : The patient with metastatic rectal cancer recieved FOLFIRI plus bevacizumab as a palliative chemotherapy and showed repetitive diarrhea despite administration of loperamide, which was treated with modified Wiryeong-tang. To evaluate the effect of the treatment, the Bristol Stool Form Scale and bowel movement frequency were checked.
Results : During the treatment, the stool form using Bristol Stool Form Scale was improved from diarrhea to normal stool, and the bowel movement frequency was decreased.
Conclusions : The result suggest that modified Wiryeong-tang may be an effective treatment for FOLFIRI-induced diarrhea.
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KEYWORD
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Chemotherapy-induced diarrhea (CID), FOLFIRI, Wiryeong-tang, Korean medicine, herbal medicine
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